Synthetic biology

Biological circuit engineering

 The biological system defines complex life phenomena such as gene expression control, metabolic pathways, and signal transmission based on networks combined with differentiated modules. The connectivity of these biological networks is similar to complex electronic circuits. One of the biggest features of biological modules is that it consists of a variety of nanodevices evolved at the molecular level to satisfy specialized functions. For example, protein synthesis, one of the most astonishing nanoscale molecular manipulations, can be accomplished by a variety of nanodevices, such as ribosome, mRNA, aminoacyl tRNA synthesis, molecular chaperones, and more. Special binding, conceptual change, and molecular catalysts also follow the laws of biological nanodevices. We are interested in designing biological circuits, biosensors, and biomaterials that can be used as medical devices, and one of our biggest goals is to create synthetic cells with redesigned gene expression, metabolic pathways, and signal transmission processes.